Use of chelerythrine and radiation for tumor therapy

Details Use of chelerythrine and radiation for tumor therapy Use of chelerythrine and radiation for tumor therapy

A - Human Necessities

61

K

A61K 31/435 (2006.01) A61K 31/4741 (2006.01) A61K 41/00 (2006.01)

Patent

CA 2284992

Combination of low doses of irradiation and chelerythrine results in increased apoptosis in tumor cells. The doses of either irradiation or chelerythrine alone are such that increased apoptosis or decreased tumor growth or proliferation would not be expected.

La combinaison d'une exposition à des rayonnements et de l'administration de chélérythrine faiblement dosés débouche sur une augmentation de l'apoptose des cellules tumorales. Les doses, s'agissant du rayonnement ou de la chélérythrine, prises isolément, sont telles que l'on n'escomptait pas une augmentation de l'apoptose ou une diminution de la prolifération de la tumeur ou de sa croissance.

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