C - Chemistry – Metallurgy – 07 – D
Patent
C - Chemistry, Metallurgy
07
D
C07D 323/00 (2006.01) A61K 31/357 (2006.01) A61K 31/395 (2006.01) A61K 31/724 (2006.01) A61P 39/04 (2006.01) C07D 257/10 (2006.01)
Patent
CA 2380920
The invention relates to the use of chemical chelators for the preparation of a medicament for the reversal of drug-induced neuromuscular block, to a kit for providing neuromuscular block and its reversal, and to cyclophane derivatives having general formula (A) wherein R is (a), (b) or (c); or general formula (B) wherein X is (a), (b) or (d), or a pharmaceutically acceptable salt thereof.
La présente invention se rapporte à l'utilisation d'agents chimiques chélatants dans la préparation d'un médicament destiné à neutraliser le blocage neuromusculaire provoqué par des médicaments, à une trousse permettant d'entraîner un blocage neuromusculaire et de neutraliser celui-ci, et à des dérivés de cyclophane de la formule générale (A) dans laquelle R est (a), (b) ou (c); ou la formule générale (B) dans laquelle X est (a), (b) ou (d), ou à un sel pharmaceutiquement acceptable des ces derniers.
Bom Antonius Helena Adolf
Muir Alan William
Rees David
Akzo Nobel N.v.
Fetherstonhaugh & Co.
N.v. Organon
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