Use of chlorine guanabenz derivatives for treating...

Details Use of chlorine guanabenz derivatives for treating... Use of chlorine guanabenz derivatives for treating...

A - Human Necessities

61

K

A61K 31/155 (2006.01)

Patent

CA 2664933

The invention relates to chlorine Guanabenz derivatives for treating Huntington' s disease and other polyglutamine expansion associated diseases. More specifically, it relates to the use of the molecule of formula (I) wherein R = H or Cl and the phenyl group is at least substituted twice, or a pharmaceutically acceptable salt thereof, for the manufacture of a medicament for treating polyglutamine expansion associated diseases.

L'invention concerne des dérivés chlorés du Guanabenz servant à traiter la maladie de Huntington et d'autres maladies associées à l'expansion de polyglutamine. Plus précisément, l'invention concerne l'utilisation de la molécule de formule (I), dans laquelle R = H ou Cl et le groupe phényle est substitué au moins deux fois, ou d'un sel acceptable du point de vue pharmaceutique de celle-ci, pour la fabrication d'un médicament servant à traiter des maladies associées à l'expansion de polyglutamine.

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