A - Human Necessities – 61 – K
Patent
A - Human Necessities
61
K
A61K 31/505 (2006.01) A61P 3/06 (2006.01) A61P 9/00 (2006.01) C07D 239/42 (2006.01)
Patent
CA 2358641
The invention concerns the use of particular oral dosages or dosage ranges of the compound (E) -7 -[4 -(4 -fluorophenyl) -6 -isopropyl -2 - [methyl(methylsulfonyl)amino]pyrimidin -5 -yl] -(3R,5S) -3,5 -dihydr oxyhept - 6 -enoic acid or a pharmaceutically acceptable salt thereof, to alter beneficially lipid levels or lipid ratios in a human patient in need thereof, as well as pharmaceutical compositions of said compound or salts adapted for oral administration which comprise such dosages, and methods of preparation thereof.
La présente invention concerne l'utilisation de posologies ou de gammes de posologie orales spécifiques du composé d'acide (E) -7 -[4 -(4 -fluorophényl) -6 -isopropyl -2 -[méthyl(méthylsulfonyl)amino]pyrimidin -5 -yl] -(3R,5S) -3,5 -dihydroxyhept -6 -énoïque ou d'un sel acceptable du point de vue pharmaceutique dudit composé, servant à modifier de manière bénéfique les niveaux de lipides ou les taux de lipides chez un patient le nécessitant. L'invention concerne également des compositions pharmaceutiques dudit composé ou des sels adaptés pour être administrés oralement et qui comprennent ces posologies, ainsi que leurs méthodes de préparation.
Astrazeneca Ab
Smart & Biggar
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