Use of chondroitinase in the manufacture of a medicament in...

Details Use of chondroitinase in the manufacture of a medicament in... Use of chondroitinase in the manufacture of a medicament in...

Category

A - Human Necessities

Subcategory

61

Subsubcategory

K

IPC codes

A61K 38/46 (2006.01) A61K 38/47 (2006.01) A61K 38/51 (2006.01) A61K 48/00 (2006.01) C12Q 1/34 (2006.01) C12Q 1/527 (2006.01) C12Q 1/68 (2006.01) G01N 11/00 (2006.01)

Type

Patent

Patent number

CA 2285940

Description

Gastrointestinal mucus from patients suffering from cystic fibrosis has been found to contain large amounts of chondroitin sulfate polymer. This finding indicates that the enzyme chondroitinase is useful for preventing gastrointestinal mucus from accumulating in cystic fibrosis patients, and subjects suffering from other diseases or conditions characterized by excess mucus secretion.

Il s'est avéré que le mucus gastro-intestinal de patients souffrant de mucoviscidose contenait de forte quantités de polymère de sulfate de chondroïtine. Cette découverte indique que la chondroïtinase est une enzyme utile s'agissant d'empêcher une accumulation de mucus gastro-intestinal chez des patients soufrant de mucoviscidose ainsi que chez des patients atteints d'autres maladies ou d'états pathologiques se caractérisant par une sécrétion excédentaire de mucus.

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