A - Human Necessities – 61 – K
Patent
A - Human Necessities
61
K
A61K 31/4355 (2006.01) A61P 9/12 (2006.01)
Patent
CA 2632931
This invention provides compositions of cicletanine and other furopyridines for treatment of elevated pulse pressure, isolated systolic hypertension, and general hypertension, in monotherapeutic forms (furopyridine-only) and in compositions combined with other antihypertensive agents, cardiovascular agents, and/or oral antidiabetic agents. Such furopyridine compositions include enantiomerically pure (positive or negative) embodiments and non- racemic enantiomeric mixtures, and include daily dosages of less than 50 mg. Further provided are methods of treatment of general or systolic hypertension, patients being administered the furopyridine compositions alone or in combination with a second agent for treatment of general hypertension or systolic hypertension, and associated complications.
La présente invention concerne des compositions de ciclétanine et d'autres furopyridines dans le traitement du pouls élevé, de l'hypertension systolique isolée et de l'hypertension générale, sous des formes monothérapeutiques (furopyridine seule) et dans des compositions combinées à d'autres agents antihypertensifs, agents cardiovasculaires et/ou agents antidiabétiques oraux. De telles compositions de furopyridine incluent des modes de réalisation énantiomériquement purs (positifs ou négatifs) et des mélanges non racémiques d'énantiomères, et incluent des dosages quotidiens inférieurs à 50 mg. L'invention concerne, en outre, des procédés destinés à traiter l'hypertension générale ou systolique, les patients recevant les compositions de furopyridine seules ou en combinaison avec un deuxième agent destiné à traiter l'hypertension générale ou l'hypertension systolique, et des complications associées.
Cornett Glenn
Page Jim
Page Karen
Cornett Glenn
Fetherstonhaugh & Co.
Navitas Pharma
Page Jim
Page Karen
LandOfFree
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