Use of co-releasing compounds for the manufacture of a...

A - Human Necessities – 61 – K

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A61K 45/06 (2006.01) A61K 31/192 (2006.01) A61K 31/28 (2006.01) A61K 31/555 (2006.01) A61K 31/616 (2006.01) A61K 31/635 (2006.01) A61K 31/663 (2006.01) A61K 33/00 (2006.01) A61K 47/48 (2006.01) A61P 9/00 (2006.01) A61P 19/02 (2006.01) A61P 25/28 (2006.01) A61P 29/00 (2006.01)

Patent

CA 2475209

Several classes of in vivo carbon monoxide-releasing compounds are useful for the treatment and/or prevention of diseases, such as chronic inflammatory, e.g. rheumatoid arthritis, and of diseases with a strong inflammatory component, such as atherosclerosis, stroke, coronary disease, and Alzheimers disease. The in vivo carbon monoxide-releasing compounds can be attached to known drug vectors and/or known anti-inflammatory drugs, such as aspirin.

Plusieurs classes de composés libérant du monoxyde de carbonein vivo sont utilisées pour traiter et/ou prévenir des maladies, telles que les inflammations chroniques, par exemple, l'arthrite rhumatoïde et des maladies à fort composant inflammatoire, telles que l'athérosclérose, les accidents vasculaires cérébraux, les maladies coronariennes, et la maladie d'Alzheimer. Les composés libérant du monoxyde de carbone in vivo peuvent être fixés sur des vecteurs de médicaments et/ou des médicaments anti-inflammatoires connus, tels que l'aspirine.

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