Use of cox-2 inhibitors for the treatment of schizophrenia,...

A - Human Necessities – 61 – K

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A61K 31/635 (2006.01) A61K 31/00 (2006.01) A61K 31/18 (2006.01) A61K 31/365 (2006.01) A61K 31/415 (2006.01) A61K 31/42 (2006.01) A61K 31/421 (2006.01) A61K 31/435 (2006.01) A61K 31/54 (2006.01) A61K 31/5415 (2006.01) A61K 31/63 (2006.01) A61K 45/06 (2006.01) A61P 25/18 (2006.01) A61P 25/24 (2006.01)

Patent

CA 2448025

The invention concerns the use of a COX-2 inhibitor for the treatment of psychiatric disorders such as schizophrenia, delusional disorders, affective disorders, autism or tic disorders, in particular chronic schizophrenic psychoses and schizoaffective psychoses, temporary acute psychotic disorders, depressive episodes, recurring depressive episodes, manic episodes and bipolar affective disorders. Moreover, the invention is concerned with the use of a COX-2 inhibitor, in particular celecoxib, in combination with a neuroleptic drug, in particular risperidone, or an antidepressant, for the treatment of psychiatric disorders such as schizophrenia, delusional disorders, affective disorders, autism or tic disorders.

La présente invention concerne l'utilisation d'un inhibiteur de cyclo-oxygénase-2 pour le traitement de troubles psychiatriques tels que la schizophrénie, les troubles délirants, les troubles affectifs, l'autisme ou les tics, notamment les psychoses schizophréniques et les psychoses schizo-affectives, les troubles psychotiques aigus temporaires, les épisodes dépressifs, les épisodes dépressifs récurrents, les épisodes maniques et les troubles affectifs bipolaires. En outre, l'invention concerne l'utilisation d'un inhibiteur de cyclo-oxygénase-2, notamment le célécoxib, en association avec un médicament neuroleptique, en particulier le rispéridone, ou un antidépresseur pour le traitement de troubles psychiatriques tels que la schizophrénie, les troubles délirants, les troubles affectifs, l'autisme et les tics.

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