Use of creatine compounds for treatment of bone or cartilage...

A - Human Necessities – 61 – K

Patent

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A61K 31/195 (2006.01) A61K 31/198 (2006.01) A61L 24/00 (2006.01) A61L 27/00 (2006.01) A61L 27/38 (2006.01) A61L 27/54 (2006.01)

Patent

CA 2338712

The method, composition and use of the composition for healing defects in bone or cartilage tissue in animals and humans caused by trauma or surgery is disclosed. The method comprises administration of creatine compounds including analogues or pharmaceutically acceptable salts thereof. Treatment in accordance with this method speeds-up time for and improves the process of healing of defects in bone or cartilage tissue in animals and humans caused by trauma or surgery including acceptance and bonding of artificial implants. The treatment with creatine compounds can be therapeutic for diseased patients, preventive for healthy people as well as geriatric for elderly people.

L'invention concerne une méthode, une composition et l'utilisation de ladite composition pour traiter, chez l'animal et chez l'homme, les défauts osseux ou cartilagineux d'origine traumatique ou chirurgicale. La méthode consiste à administrer des composés à base de créatine, y compris leurs analogues ou leurs sels pharmaceutiquement acceptables. Le traitement selon cette méthode accélère et améliore, chez l'animal et chez l'homme, la réparation des défauts du tissu osseux ou cartilagineux d'origine traumatique ou chirurgicale, et notamment l'acceptation et la fixation des implants artificiels. Ce traitement peut être soit thérapeutique chez les malades, soit préventif chez les sujets sains, soit gériatrique chez les personnes âgées.

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