Use of creatine or creatine compounds for skin preservation

Details Use of creatine or creatine compounds for skin preservation Use of creatine or creatine compounds for skin preservation

A - Human Necessities

61

K

A61K 31/195 (2006.01) A61K 31/155 (2006.01) A61K 31/198 (2006.01)

Patent

CA 2376943

The present invention relates to the use of creating compounds such as, for example, creatine, creatine phosphate or analogs of creatine, such as creatine-pyruvate, creatine-ascorbate, cyclocreatine, 3 guanidinopropionic acid, guanidinoacetate, homocyclocreatine, guanidino benzoates as energy generating systems and antioxidants for preservation of skin against adverse aging effects and damage secondary to insults such as harmful sun radiations, stress and fatigue. The creatine compounds which can be used in the present method include (1) creatine, creatine phosphate and analogs of these compounds which can act as substrates or substrate analogs for creatine kinase; (2) molecules that mimic the biological activity of creatine (3) molecules that modulate the creatine kinase system.

La présente invention concerne l'utilisation de composés de créatine tels que, par exemple, la créatine, le phosphate de créatine ou des analogues de la créatine, par exemple la créatine-pyruvate, la créatine-ascorbate, la cyclocréatine, l'acide 3-guanidinopropionique, la guanidinoacétate, l'homocyclocréatine, les guanidinobenzoates, comme systèmes exergoniques et antioxydants permettant de préserver la peau contre les effets indésirables du vieillissement et les dommages secondaires liés aux attaques extérieures nuisibles telles que les rayons de soleil, le stress et la fatigue. Parmi les composés de créatine pouvant être utilisés dans la présente méthode se trouvent (1) la créatine, le phosphate de créatine et des analogues de ces composés pouvant agir comme substrats ou analogues de substrats pour la créatine kinase, (2) des molécules imitant l'activité biologique de la créatine (3), et des molécules modulant le système de la créatine kinase.

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