Use of cxcl6 chemokine in the prevention or repair of...

A - Human Necessities – 61 – K

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A61K 38/19 (2006.01) A61P 19/00 (2006.01)

Patent

CA 2533124

The present invention disclosed the expression of CXCL6 by cells which are able to form stable cartilage. The invention describes the use of these cells and of CXCL6 to promote cartilage (and underlying bone) formation e.g. in the repair of cartilage or osteochondral defects. The invention further describes the use of chemokines in the modulation of progenitor cell differentiation.

La présente invention concerne l'expression de CXCL6 par des cellules qui sont capables de former un cartilage stable. L'invention décrit l'utilisation de ces cellules et de CXCL6 pour promouvoir la formation du cartilage (et de l'os sous-jacent), dans la réparation du cartilage ou de défauts ostéochondraux, par exemple. L'invention concerne également l'utilisation de chimiokines dans la modulation de la différenciation de cellules progénitrices.

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