C - Chemistry – Metallurgy – 07 – K
Patent
C - Chemistry, Metallurgy
07
K
C07K 1/13 (2006.01) A61K 51/04 (2006.01) C07B 59/00 (2006.01) C07F 17/00 (2006.01) C07J 41/00 (2006.01) G01N 33/534 (2006.01)
Patent
CA 2160979
The invention relates to the use of radioactive metallocene carboxylic acids and their derivatives of formula I, Image (I) in which R1, R2, R3, R4 and R5 have different meanings, and M stands for a radioactive metal isotope of the elements of atomic numbers 21-29, 31, 42-44, 49 or 57-83, for radioactive labeling of NH- active compounds, a process for labeling the latter, as well as new metallocene carboxylic acid derivatives of formula I with M meaning a Cr-51, Mn-52, Ru-97, Ru-103, Re-186, Re-188, Ir-191 isotope.
Bereskin & Parr Llp/s.e.n.c.r.l.,s.r.l.
Institut Fur Diagnostikforschung Gmbh
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