A - Human Necessities – 61 – K
Patent
A - Human Necessities
61
K
A61K 31/4545 (2006.01) A61K 31/195 (2006.01) A61K 31/198 (2006.01) A61K 31/277 (2006.01)
Patent
CA 2487529
The present invention relates to the use of compounds and compositions of compounds having D4 and 5-HT2A antagonistic, partial agonistic or inverse agonistic activity for the treatment of the underlying dysregulation of the emotional functionality of mental disorders (i.e. affect instability - hypersensitivity - hyperaesthesia - dissociative phenomena - etc). The invention also relates to methods comprising administering to a patient diagnosed as having a neuropsychiatric disorder a pharmaceutical composition containing (i) compounds having D4 antagonistic, partial agonistic or inverse agonistic activity and (ii) compounds having 5-HT2A antagonistic, partial agonistic or inverse agonistic, and (iii) any known medicinal compound and compositions of said compounds. The combined D4 and 5- HT2A antagonistic, partial agonistic or inverse agonistic effects may reside within the same chemical or biological compound or in two different chemical and/or biological compounds.
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Pharmaneuroboost N.v.
Smart & Biggar
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