Use of defibrinated blood for manufacture of a...

Details Use of defibrinated blood for manufacture of a... Use of defibrinated blood for manufacture of a...

C - Chemistry, Metallurgy

07

K

C07K 14/805 (2006.01) A61K 38/42 (2006.01) C07K 1/02 (2006.01) C07K 1/30 (2006.01) C07K 1/34 (2006.01) C12N 5/078 (2010.01)

Patent

CA 2756609

Red blood cells are purified by defibrinating whole blood and then filtering the defibrinated whole blood, whereby at least a portion of a plasma component is separated from the red blood cells to form a suspension of red blood cells, thereby purifying the red blood cells. Whole blood is defibrinated by, for example, using a chemical coagulating agent or mechanical agitation. Separation of the plasma component from red blood cells can be completed by, for example, diafiltration. The suspension of red blood cells can then be employed to produce a hemoglobin-based oxygen carrier.

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