Use of defibrotide and at least one haematopoietic factor to...

A - Human Necessities – 61 – K

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A61K 38/19 (2006.01) C12N 5/078 (2010.01) A61K 31/70 (2006.01) A61K 31/711 (2006.01) A61P 7/00 (2006.01)

Patent

CA 2406179

A description is given of a method of increasing the amount of stem cells and progenitor cells in the peripheral blood of a mammal; the method is characterised by the administration of defibrotide in combination or in temporal proximity with at least one haematopoietic factor, (preferably G-CSF) having the capacity to mobilise haematopoietic progenitors.

L'invention concerne un procédé pour augmenter la quantité de cellules embryonnaires et de cellules souches dans le sang périphérique d'un mammifère. Ce procédé se caractérise par l'administration de défibrotide rapprochée dans le temps ou combinée à au moins un facteur hématopoïétique (de préférence G-CSF) ayant la faculté de mobiliser des précurseurs hématopoïétiques.

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