Use of dichlorobenzyl alcohol for preparing a preparation...

A - Human Necessities – 61 – K

Patent

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A61K 31/045 (2006.01) A61P 29/00 (2006.01)

Patent

CA 2277207

The present invention relates to use of dichlorobenzyl alcohol for preparing a preparation for topical treatment of inflammation and the preparation for this purpose. It is known to use dichlorobenzyl alcohol (2,4-DCBA) as an agent against bacteria and fungi, i.e. as a desinfectant. By the present invention it has, however, suprisingly turned out that dichlorobenzyl alcohol, preferably 2,4-dichlorobenzyl alcohol, is also useful for treatment of inflammation. The invention also relates to a preparation containing dichlorobenzyl alcohol, preferably 2,4-dichlorobenzyl alcohol, for topical treatment of inflamation, which can be applied onto skin or mucosa in the form of an ointment, a cream, a gel or a solution. Thus, the preparation has turned out to be effective against a variety of inflammatory conditions including skin diseases, such as pruritus and psoriasis, insect bite/sting etc.

L'invention concene l'utilisation d'alcool dichlorobenzylique pour réaliser une préparation pour le traitement topique des inflammations et une préparation correspondante. On connaît l'utilisation d'alcool dichlorobenzylique (2,4-DCBA) comme agent antibactérien et antifongique, notamment comme désinfectant. L'invention porte sur l'action nouvellement découverte et surprenante de l'alcool dichlorobenzylique, de préférence de l'alcool 2,4-dichlorobenzylique, dans le traitement des inflammations. L'invention concerne en outre une préparation sous forme d'onguent, de crème, de gel ou de solution contenant de l'alcool dichlorobenzylique, de préférence de l'alcool 2,4-dichlorobenzylique, pouvant être appliquée sur la peau et les muqueuses, s'utilisant dans le traitement topique des inflammations. Cette préparation s'est avérée efficace contre diverses affections inflammatoires, y compris les maladies de la peau telles que le prurit et le psoriasis, les piqûres d'insectes, etc.

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