Use of dronedarone for preparing a medicament for the...

Details Use of dronedarone for preparing a medicament for the... Use of dronedarone for preparing a medicament for the...

A - Human Necessities

61

K

A61K 31/343 (2006.01) A61K 45/06 (2006.01) A61P 9/06 (2006.01) A61P 43/00 (2006.01)

Patent

CA 2722815

Use of dronedarone or one of its pharmaceutically acceptable salts for preparing a medicament for the treatment of patients with arrhythmia, said patients having an increase of creatinine level due to dronedarone administration, said creatinine level increasing following dronedarone treatment initiation, said creatinine level increase reaching a plateau and being used as a new baseline, said creatinine level increase being reversible after dronedarone discontinuation.

La présente invention concerne lutilisation de dronédarone, ou de lun de ses sels pharmaceutiquement acceptables, dans la préparation dun médicament destiné à traiter des patients souffrant darythmie. Lesdits patients présentent une augmentation du niveau de la créatinine due à ladministration de dronédarone, ledit niveau de créatinine augmentant suite à linitiation dun traitement à la dronédarone. Ladite augmentation du niveau de créatinine atteint un plateau et est utilisée en tant que nouvelle ligne de base. Cette augmentation est réversible après larrêt de la dronédarone.

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