Use of edg receptor binding agents in cancer

Details Use of edg receptor binding agents in cancer Use of edg receptor binding agents in cancer

A - Human Necessities

61

K

A61K 31/135 (2006.01) A61K 31/381 (2006.01) A61P 35/00 (2006.01)

Patent

CA 2483594

Provided is a method for treating solid tumors, e.g. tumor invasiveness, and particularly inhibiting or controlling deregulated angiogenesis, using a sphingosine-1-phosphate receptor agonist, optionally in combination with a chemotherapeutic agent. The invention also comprises a combination of a sphingosine-1-phosphate receptor agonist with a chemotherapeutic agent.

L'invention concerne un procédé de traitement de tumeurs solides, notamment le pouvoir envahissant de la tumeur, et notamment l'inhibition ou le contrôle de l'angiogénèse déréglée, à l'aide d'un agoniste du récepteur de sphingosine-1-phosphate, éventuellement en association avec un agent chimiothérapeutique. L'invention concerne également une association d'un agoniste du récepteur de sphingosine-1-phosphate avec un agent chimiothérapeutique.

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