Use of edible acid in fast-dispersing pharmaceutical solid...

Details Use of edible acid in fast-dispersing pharmaceutical solid... Use of edible acid in fast-dispersing pharmaceutical solid...

A - Human Necessities

61

K

A61K 9/22 (2006.01) A61K 9/20 (2006.01) A61K 9/46 (2006.01) A61K 9/64 (2006.01) A61K 31/415 (2006.01)

Patent

CA 2514650

In order to reduce the disintegration time of solid, oral, fast-dispersing, lyophilized, pharmaceutical dosage forms, an edible acid such as citric acid is included in a composition used to produce said dosage forms where there is a pharmaceutically active ingredient having a low water solubility.

Selon la présente invention, on ajoute à une composition utilisée dans la production de formes posologiques pharmaceutiques solides orales lyophilisées à dispersion rapide, un acide comestible tel que l'acide citrique afin de réduire le temps de désintégration desdites formes posologiques, lesquelles renferment un ingrédient pharmaceutiquement actif possédant une faible solubilité dans l'eau.

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