A - Human Necessities – 61 – K
Patent
A - Human Necessities
61
K
A61K 31/415 (2006.01) A61K 31/4178 (2006.01)
Patent
CA 2166781
Use of a compound of general formula (I) wherein R1 is a hydrogen atom, a linear or branched C1-C6 alkyl radical, R2 is a hydrogen atom, a methyl, chloro, bromo or fluoro group, and R3 is a hydrogen atom, a methyl, hydroxy, methoxy, fluoro, chloro or bromo group, and its therapeutically acceptable salts, its racemic or optically active isomers, for the preparation of a drug for treating Alzheimer-like senile dementia, pre-Alzheimer syndrome, progressive supranuclear palsy and other neurodegenerative diseases.
La présente invention concerne l'utilisation d'un com- posé de formule générale (I) dans laquelle Représente un atome d'hydrogène, un radical alkyle linéaire ou ramifié en C1-C6, R2 représente un atome d'hydrogène, un groupe méthyle, chloro, bromo ou fluoro, et R3 représente un atome d'hydrogène, un groupe méthyle, hydroxy, méthoxy, fluoro, chloro ou bromo, ses sels thérapeutiquement acceptables, son racémique ou ses isomères optiquement actifs, pour la préparation d'un médicament destiné au traitement de la démence sénile du type Alzheimer, du syndrome pré-Alzheimer, de la paralysie supra nucléaire progressive et d'autres maladies neurodégénératives.
Briley Michael
Colpaert Francis
Imbert Thierry
Norton Rose Or S.e.n.c.r.l. S.r.l./llp
Pierre Fabre Medicament
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