Use of ep2 selective receptor agonists in medical treatment

Details Use of ep2 selective receptor agonists in medical treatment Use of ep2 selective receptor agonists in medical treatment

A - Human Necessities

61

K

A61K 31/44 (2006.01) A61K 45/00 (2006.01) A61P 1/04 (2006.01) A61P 9/02 (2006.01) A61P 19/00 (2006.01) A61P 27/06 (2006.01)

Patent

CA 2518193

The present invention relates to methods of treating pulmonary hypertension, facilitating joint fusion, facilitating tendon and ligament repair, reducing the occurrence of secondary fracture, treating avascular necrosis, facilitating cartilage repair, facilitating bone healing after limb transplantation, facilitating liver regeneration, facilitating wound healing, reducing the occurrence of gastric ulceration, treating hypertension, facilitating the growth of tooth enamel or finger or toe nails, treating glaucoma, treating ocular hypertension, and repairing damage caused by metastatic bone disease using an EP2 selective receptor agonist.

La présente invention se rapporte à des méthodes destinées à traiter l'hypertension artérielle pulmonaire, à faciliter la fusion articulaire, à faciliter la réparation des tendons et des ligaments, à réduire l'apparition de fractures secondaires, à traiter la nécrose avasculaire, à faciliter la réparation du cartilage, la cicatrisation des os suite à une transplantation d'un membre, la régénération du foie et la cicatrisation des plaies, à réduire l'apparition d'ulcérations gastriques, à traiter l'hypertension artérielle, à faciliter la croissance de l'émail dentaire ou des ongles des doigts ou des orteils, à traiter les glaucomes et l'hypertension oculaire et à réparer les lésions dues aux affections osseuses métastatiques au moyen d'un agoniste sélectif du récepteur EP¿2?.

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