A - Human Necessities – 61 – K
Patent
A - Human Necessities
61
K
A61K 31/427 (2006.01) A61P 25/00 (2006.01) A61P 25/16 (2006.01) A61P 25/28 (2006.01) A61P 27/00 (2006.01)
Patent
CA 2722371
Methods of treating Tau-associated diseases, preferably tauopathies, are described using epothilone D that exhibit good brain penetration, long half- life, and high selective retention in brain, and provides effective therapies in treating tauopathies including Alzheimer's disease.
Cette invention concerne des procédés pour traiter les maladies associées à la protéine tau, de préférence les tauopathies, au moyen de l'épothilone D qui possède une bonne pénétration dans le cerveau, une longue demi-vie, et une rétention sélective élevée dans le cerveau, et qui fournit des thérapies efficaces dans le traitement des tauopathies, y compris la maladie d'Alzheimer.
Albright Charles F.
Barten Donna Marie
Lee Francis Y.
Bristol-Myers Squibb Company
Gowling Lafleur Henderson Llp
LandOfFree
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