A - Human Necessities – 61 – K
Patent
A - Human Necessities
61
K
A61K 38/17 (2006.01) A61K 39/008 (2006.01) A61K 48/00 (2006.01) C12N 5/10 (2006.01) A61K 35/12 (2006.01) C12N 5/06 (2006.01)
Patent
CA 2269034
Disclosed are the use of FasL as active pharmacological component in the treatment of TH1/TH2 diseases, compositions containing FasL and one or more cytokines, specially interferon-.gamma., the use of a composition according to claims 11 and 12 for the treatment of TH1/TH2 diseases, the use of autologous Cd4+/FasL-/TH1 cell lines of the patient, transfected with the FasL gene sequence or with physiologically active fragments of the FasL gene sequence for the treatment of TH1/TH2 diseases.
L'invention concerne l'utilisation de ligands Fas(FasL) comme principe pharmacologique actif pour le traitement de maladies mettant en jeu les cellules TH1/TH2, une composition contenant des ligands Fas et au moins une cytokine, notamment l'interféron gamma , l'utilisation d'une composition selon la revendication 11 ou 12 pour le traitement de maladies mettant en jeu les cellules TH1/TH2, l'utilisation de lignées cellulaires CD4<+>/FasL<->/TH1 autologues du patient transfectées avec la séquence génique FasL ou avec des fragments physiologiquement actifs de la séquence génique FasL pour lutter contre les maladies mettant en jeu les TH1/TH2.
Da Conceicao-Silva Fatima
Hahne Michael
Schroter Michael
Tschopp Jurg
Apotech S.a.
Da Conceicao-Silva Fatima
Hahne Michael
Ridout & Maybee Llp
Schroter Michael
LandOfFree
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