Use of fibroblast growth factor 7 (fgf7) and of the receptor...

Details Use of fibroblast growth factor 7 (fgf7) and of the receptor... Use of fibroblast growth factor 7 (fgf7) and of the receptor...

G - Physics

01

N

G01N 33/74 (2006.01)

Patent

CA 2688480

The use of fibroblast growth factor Fgf7 and of the corresponding receptor Fgfr2b as biomarker candidates for the progesterone receptor antagonist 11 .beta.-(4-acetylphenyl)- 17.beta.-hydroxy-17.alpha.-(1,1,2,2,2-pentafIuoroethyl)estra-4,9-dien-3-one, also known under the designations ZK230211 or ZK-PRA, of the Formula (I) and for antiestrogens is described.

L'invention porte sur l'utilisation du facteur de croissance des fibroblastes Fgf7 et du récepteur correspondant Fgfr2b en tant que candidats de biomarqueur pour l'antagoniste des récepteurs de la progestérone 11 .beta.-(4-acétylphényl)-17.beta.-hydroxy-17.alpha.-(1,1,2,2,2-pentafIuoroéthyl)estra-4,9-diène-3-one, également connu sous les dénominations ZK230211 ou ZK-PRA, représentée par la Formule (I) et pour des anti-AEstrogènes.

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