Use of fibroblast growth factors to stimulate bone growth

A - Human Necessities – 61 – K

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A61K 38/18 (2006.01) A61K 31/727 (2006.01)

Patent

CA 2184916

The present invention provides therapeutic compositions for the prevention and treatment of pathological conditions involving bone and dental tissue. The present invention also provides a method to promote bone repair and/or growth for the treatment of pathological conditions involving bone tissue, for example, osteoporosis, Paget's disease, osteopetrosis, and periodontal disease and fracture repair, and healing of bone defects by administering FGF-I to an animal or human in need of said treatment.

La présente invention se rapporte à des compositions thérapeutiques destinées à la prévention et au traitement d'états pathologiques impliquant les tissus osseux et dentaires. La présente invention se rapporte également à un procédé destiné à promouvoir la consolidation et/ou la croissance osseuse, pour le traitement d'états pathologiques impliquant les tissus osseux, par exemple, l'ostéoporose, la maladie de Paget, la maladie d'Albers-Schonberg et la parodontolyse, ainsi que pour la consolidation des fractures et le traitement de anomalies osseuses, ce procédé consistant à administrer, à un animal ou humain nécessitant un tel traitement, le facteur de croissance de fibroblaste 1.

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