C - Chemistry – Metallurgy – 12 – Q
Patent
C - Chemistry, Metallurgy
12
Q
C12Q 1/26 (2006.01) C12Q 1/32 (2006.01) G01N 1/00 (2006.01)
Patent
CA 2051119
2051119 9012113 PCTABS00002 Systems and methods are disclosed for removing redox-active substances from aqueous, partially aqueous or non-aqueous fluids. The invention involves contacting the fluid to be treated with a redox-active agent that is insoluble in the fluid, thereby oxidizing interfering redox-active substances. Electron transfer agents can also be employed. The residual redox oxidizing agent is removed from the treated fluid on the basis of its insolubility, so that no residual redox activity remains. The invention is useful for removal of interfering redox-active substances from liquid samples when analytes in the sample are to be measured using reduction-oxidation chemistry and the redox-active interfering substances removed by the disclosed method interfere in the reduction-oxidation analysis. Furthermore, this invention is especially useful to pretreat blood, serum, plasma or other bodily fluids prior to analysis or other use of these fluids, where the presence of reduction-oxidation active substances constitutes an interference in that analysis or use.
Daubney Stephan D.
Johnston James B.
Palmer John L.
Blake Cassels & Graydon Llp
Daubney Stephan D.
Enzymatics Inc.
Johnston James B.
Palmer John L.
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