C - Chemistry – Metallurgy – 07 – D
Patent
C - Chemistry, Metallurgy
07
D
C07D 491/04 (2006.01) A61K 31/407 (2006.01) A61P 25/00 (2006.01) C07D 495/04 (2006.01)
Patent
CA 2624795
The present invention provides the use of fused pyrrole carboxylic acids of formula (I) for the manufacture of a medicament to inhibit D-amino acid oxidase, particularly for the treatment of neurodegenerative and psychiatric disorders or diseases; certain compounds of formula I being novel, pharmaceutical compositions containing them, their use in medicine and methods of treatment using them are also disclosed.
La présente invention concerne l'emploi d'acides carboxyliques à cycles pyrrole fusionnés de formule (I) dans la fabrication d'un médicament destiné à inhiber la D-acide aminé oxydase, en particulier dans le traitement de troubles ou de maladies neurodégénératifs et psychiatriques ; certains composés de formule I étant nouveaux, la présente invention concerne également les préparations pharmaceutiques les contenant, leur emploi en thérapie et les méthodes de traitement les employant.
Brandish Philip E.
Brandon Nicholas
Campbell Alister
Pike Andrew
Sparey Timothy
Merck & Co. Inc.
Merck Sharp & Dohme Corp.
Merck Sharp & Dohme Limited
Norton Rose Or S.e.n.c.r.l. S.r.l./llp
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