Use of fviia or a tissue factor antagonist for regulating...

A - Human Necessities – 61 – K

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A61K 38/36 (2006.01)

Patent

CA 2378249

The present invention relates to use of FVII and/or FVIIa and/or another TF agonist and/or FVIIai and/or another TF antagonist in therapeutic treatment of pathological conditions that can be related to cell migration or treated by specific regulation of cell migration or chemotaxis. The invention also relates to the use of FVII and/or FVIIa and/or another TF agonist and/or FVIIai and/or another TF antagonist in therapeutic treatment of pathological conditions that can be related to regulation of expression of at least one gene in a cell, e.g., Cyr61gene.

L'invention concerne l'utilisation d'un agoniste TF et/ou FVII et/ou FVIIa, et/ou d'un antagoniste TF et/ou FVIIai, dans le traitement thérapeutique d'états pathologiques pouvant être associés à la migration cellulaire, ou traités par régulation spécifique de la migration cellulaire ou chimiotaxie. L'invention concerne également l'utilisation d'un agoniste TF et/ou FVII et/ou FVIIa, et/ou d'un antagoniste TF et/ou FVIIai dans le traitement d'états pathologiques pouvant être associés à la régulation de l'expression d'au moins un gène dans une cellule, par exemple le gène Cyr61.

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