A - Human Necessities – 61 – K
Patent
A - Human Necessities
61
K
A61K 31/55 (2006.01) A61K 31/695 (2006.01) A61P 3/10 (2006.01) A61P 9/10 (2006.01) A61P 25/00 (2006.01) A61P 25/08 (2006.01) A61P 25/14 (2006.01) A61P 25/16 (2006.01) A61P 25/28 (2006.01)
Patent
CA 2506282
The invention relates to the use of galanthamine and the cholinergically active derivatives thereof in the production of medicaments for preventive treatment of postoperative delirium and/or subsyndronal postoperative delirium.Galanthamine, the galathamine derivative(4aS, 6R, 8aS)-6-hydroxy-3- methoxy-11-methyl-4a,5,9,10-tetrahydro-6H-benzofuro[3a, 3, 2-ef] [2]benzazepinium bromide and analogous salts, hydrates or solvates are advantageously suited for use according to the invention.
La présente invention concerne l'utilisation de galanthamine et de ses dérivés ayant une activité cholinergique, pour préparer des produits pharmaceutiques utilisés pour le traitement et le traitement préventif du délire postopératoire et/ou du délire postopératoire sous-syndromal. En plus de la galanthamine, le dérivé de galanthamine bromure de (4aS, 6R, 8aS)-6-hydroxy-3-méthoxy-11-méthyl-4a,5,9,10-tétrahydro-6H-benzofuro[3a, 3, 2-ef] [2]benzazepine, et des sels, hydrates ou solvates analogues, conviennent pour l'utilisation décrite dans l'invention.
Bodenteich Angelika
Czollner Laszlo
Frantsits Werner J.
Pirich Eberhard
Borden Ladner Gervais Llp
Sanochemia Pharmazeutika Ag
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