Use of gallium to treat biofilm-associated infectons

A - Human Necessities – 61 – K

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Details

A61K 33/24 (2006.01) A61P 31/04 (2006.01)

Patent

CA 2637378

The invention provides methods, compositions, and kits for treatment or prevention of biofilm-associated infections in an individual. Methods of the invention include administration of a gallium-containing composition for treatment of an established biofilm or prevention of formation of a biofilm. Some methods include administration of a gallium-containing composition in conjunction with an antibiotic substance. Some methods include treatment or prevention of an orally-associated biofilm with a gallium-containing composition in the form of a dentrifice, mouthwash, or chewing gum composition.

La présente invention concerne des procédés, des compositions, et des trousses pour le traitement ou la prévention d'infections associées aux films biologiques chez un sujet. Des procédés de l'invention comprennent l'administration d'une composition contenant du gallium pour le traitement d'un film biologique établi ou la prévention de formation de film biologique. Certains procédés comprennent l'administration d'une composition contenant du gallium conjointement avec une substance antibiotique. Certains procédés comprennent le traitement ou la prévention d'un film biologique d'association orale avec une composition contenant du gallium sous la forme d'une composition de dentifrice, de bain de bouche, ou de gomme à mâcher.

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