Use of genes differentially expressed during aging of liver...

Details Use of genes differentially expressed during aging of liver... Use of genes differentially expressed during aging of liver...

A - Human Necessities

61

K

A61K 38/00 (2006.01) A61K 48/00 (2006.01) A61P 39/00 (2006.01) C12Q 1/68 (2006.01)

Patent

CA 2527957

Mouse genes differentially expressed in comparisons of older and younger livers by gene chip analysis have been identified, as have corresponding human genes and proteins. The human molecules, or antagonists thereof, may be used for protection against faster-than-normal biological aging, or to achieve slower-than-normal biological aging. The human molecules may also be used as markers of biological aging.

Des gènes de souris exprimés différemment dans des foies jeunes et vieux, comme le montrent des comparaisons réalisées à l'aide d'analyses faisant appel à des puces à ADN, ainsi que des gènes et protéines humain(e)s correspondant(e)s ont été identifiés. Les molécules humaines, ou leurs antagonistes, peuvent être utilisé(e)s pour assurer une protection contre un vieillissement biologique plus rapide que la normale, ou pour permettre un vieillissement biologique plus lent que la normale. Lesdites molécules humaines peuvent en outre servir de marqueurs du vieillissement biologique.

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