Use of genetically modified cells to treat defects, disease...

A - Human Necessities – 61 – K

Patent

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A61K 35/12 (2006.01) A61K 38/18 (2006.01) A61K 38/44 (2006.01) C07K 14/48 (2006.01) C12N 9/02 (2006.01) C12N 9/10 (2006.01) C12N 9/12 (2006.01) A61K 38/00 (2006.01) A61K 48/00 (2006.01)

Patent

CA 2095300

Methods of genetically modifying donor cells by gene transfer for grafting into the central nervous system to treat defective, Diseased or damaged cells are disclosed. The modified donor cells produce functional molecules that effect the recovery or improved function of cells in the CNS. Methods and vectors for carrying out gene transfer and grafting are described.

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