Use of genomic testing and ketogenic compounds for treatment...

Details Use of genomic testing and ketogenic compounds for treatment... Use of genomic testing and ketogenic compounds for treatment...

C - Chemistry, Metallurgy

12

Q

C12Q 1/68 (2006.01) A61K 31/12 (2006.01) G01N 33/68 (2006.01) C40B 30/00 (2006.01)

Patent

CA 2694925

Methods of using genotyping to select patients for treatment with compounds capable of elevating ketone body concentrations in amounts effective to treat reduced neuronal metabolism associated with reduced neuronal metabolism are disclosed. Conditions include Alzheimer's disease, Parkinson's Disease, Friedreich's Ataxia, GLUTI-deficient Epilepsy, Leprechaunism, and Rabson- Mendenhall Syndrome, Coronary Arterial Bypass Graft, dementia, anesthesia-induced memory loss, and Huntington's Disease.

Cette invention concerne des procédés d'utilisation d'un génotypage pour sélectionner des patients pour le traitement avec des composés capables d'élever les concentrations du corps en cétone en des quantités efficaces pour traiter une fonction cognitive réduite associée à un métabolisme neuronal réduit, par exemple la maladie d'Alzheimer.

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