Use of ghrelin and unacylated ghrelin compostions in...

Details Use of ghrelin and unacylated ghrelin compostions in... Use of ghrelin and unacylated ghrelin compostions in...

A - Human Necessities

61

K

A61K 38/25 (2006.01) A61P 3/10 (2006.01)

Patent

CA 2543507

A novel combination of ghrelin and unacylated ghrelin is described herein. Methods of administering and uses of this combination to alter an insulin- associated parameter are also described. Compositions and packages containing ghrelin and/or one of its analogs and nonacylated ghrelin and/or one of its analogs as well as the uses of such compositions in providing therapeutic benefit to human patients diagnosed with for example insulin resistance, diabetes and obesity are described.

L'invention concerne une nouvelle combinaison de ghréline et de ghréline non acylée, ainsi que des procédés d'administration et d'utilisation de cette combinaison afin de modifier un paramètre associé à l'insuline. Cette invention concerne également des compositions et des conditionnements contenant de la ghréline et/ou un des ses analogues ou de la ghréline non acylée et/ou un de ses analogues, ainsi que les utilisations de ces compositions afin de fournir un avantage thérapeutique à des patients humains diagnostiqués avec, par exemple, une résistance à l'insuline, du diabète ou de l'obésité.

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