Use of glp-1 and agonists thereof to prevent cardiac myocyte...

A - Human Necessities – 61 – K

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A61K 38/26 (2006.01)

Patent

CA 2599594

The present invention relates generally to the novel use of GLP-1, including analogs, and agonists, to prevent cardiac myocyte apoptosis. The present invention relates to methods for using GLP-1 for the treatment of conditions associated with cardiac myocyte apoptosis. The present invention further relates to improving the efficiency of cardiac myocytes and also to improving cardiac contractility.

La présente invention concerne d'une manière générale une nouvelle utilisation de GLP-1, notamment d'analogues et d'agonistes de façon à prévenir l'apoptose de myocytes cardiaques. Cette invention concerne des techniques d'utilisation de GLP-1 destinées à traiter des états associés à l'apoptose de myocytes cardiaques. Cette invention concerne aussi l'amélioration de l'efficacité des myocyte cardiaques et l'amélioration de la contractilité cardiaque.

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