Use of glucose-6-phosphate isomerase and antibodies thereto...

A - Human Necessities – 61 – K

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Details

A61K 38/52 (2006.01) C07K 14/46 (2006.01) C07K 16/40 (2006.01) C12N 5/16 (2006.01) C12N 15/63 (2006.01) G01N 33/53 (2006.01) G01N 33/564 (2006.01) A61K 38/00 (2006.01)

Patent

CA 2370867

The present invention relates to the use of antibodies against glucose-6- phosphate isomerase (GPI) and like protein for diagnosis of arthritis and the use of said protein for treatment of arthritis. It is also aimed at a process for isolating monoclonal antibodies capable of transferring arthritis and antibodies thereof, as well as a method for determining the anti-arthritic potential of a composition.

La présente invention concerne l'utilisation d'anticorps dirigés contre la 6-phosphate isomerase (GPI) et de protéines analogues pour le diagnostic de l'arthrite et l'utilisation de ladite protéine pour le traitement de cette pathologie. L'invention concerne également un procédé permettant d'isoler des anticorps monoclonaux capables de transférer l'arthrite et ses anticorps, ainsi qu'une méthode de détermination du potentiel anti-arthritique de la composition.

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