Use of glucose uptake enhancer for reducing apoptosis

Details Use of glucose uptake enhancer for reducing apoptosis Use of glucose uptake enhancer for reducing apoptosis

A - Human Necessities

61

K

A61K 31/00 (2006.01) A61K 31/425 (2006.01) A61K 31/426 (2006.01) A61K 31/427 (2006.01) A61K 31/44 (2006.01) A61K 31/4439 (2006.01) A61K 45/00 (2006.01) A61P 9/00 (2006.01) A61P 9/10 (2006.01) A61P 43/00 (2006.01)

Patent

CA 2338211

A method for reducing or preventing apoptosis of differentiated cells selected from the list consisting of cardiac myocytes, pancreatic beta cells, endothelial cells and neuronal cells in the human or non-human mammal, which method comprises administration, including acute administration, of an effective, non-toxic amount of a glucose uptake enhancer to a human or non- human mammal in need thereof.

L'invention se rapporte à un procédé permettant de réduire ou de prévenir l'apoptose de cellules différenciées sélectionnées parmi des myocytes cardiaques, des cellules pancréatiques bêta, des cellules endothéliales et des cellules neuronales chez des mammifères humains ou non humains. Ledit procédé consiste en l'administration, et notamment en l'administration aiguë, d'une quantité efficace, non toxique, d'un activateur d'assimilation du glucose à un mammifère humain ou non humain nécessitant un tel traitement.

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