Use of glucosidase inhibitors for therapy of mucovisidosis

Details Use of glucosidase inhibitors for therapy of mucovisidosis Use of glucosidase inhibitors for therapy of mucovisidosis

A - Human Necessities

61

K

A61K 31/352 (2006.01) A61K 31/4375 (2006.01)

Patent

CA 2545133

The invention relates to the use of glycosidase inhibitors selected from compounds of general formula (1), wherein R¿1? represents a CH¿3? group, or CH¿2?OH, R¿2? represents H or an alkyl group having 1-5 carbon atoms, or R¿1? and R¿2? together form a group having formula (II), with carbon in position (a) and nitrogen of formula (I) mentioned above, for the preparation of a medicament used to treat mucovisidosis.

La présente invention a pour objet l'utilisation d'inhibiteurs de glucosidase choisis notamment parmi les composés de formule générale (I) suivante : dans laquelle - Ri représente un groupe CH3, ou CH2OH, - R2 représente H ou un groupe alkyle de 1 à 5 atomes de carbone, - ou RI et R2 forment ensemble avec la carbone en position (a) et l'azote de la formule (I) ci-dessus un groupe de formule (II): pour la préparation d'un médicament destiné au traitement de la mucoviscidose.

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