Use of grf1 protein and cells expressing grf1 protein for...

Details Use of grf1 protein and cells expressing grf1 protein for... Use of grf1 protein and cells expressing grf1 protein for...

G - Physics

01

N

G01N 33/68 (2006.01)

Patent

CA 2418655

The invention concerns the use of whole or part of the GRF1 protein, or of cells expressing whole or part of the GRF1 protein, in methods for detecting compounds for preventing and/or treating pathologies or disorders of the central nervous system involving neuronal death, such as apoptosis, or related to leptin metabolism. The pathologies of the central nervous system are in particular cerebral ischemia, Parkinson's disease or Alzheimer's disease.

Utilisation de tout ou partie de la protéine GRF1, ou de cellules exprimant tout ou partie de la protéine GRF1, dans des procédés de détection de composés destinés à la prévention et / ou au traitement de pathologies ou de désordres du système nerveux central impliquant une mort neuronale, telle que l'apoptose, ou liés au métabolisme de la leptine. Les pathologies du système nerveux central sont notamment l'ischémie cérébrale, la maladie de Parkinson ou la maladie d'Alzheimer.

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