A - Human Necessities – 61 – K
Patent
A - Human Necessities
61
K
A61K 31/55 (2006.01) A61P 21/00 (2006.01) A61P 25/00 (2006.01)
Patent
CA 2631121
The invention concerns the use of guanabenz and its derivatives for making drugs for treating cystic fibrosis and diseases related to a protein addressing deficiency in the cells, said derivatives corresponding to formula (I), wherein: R = H or Cl and the phenyl group comprises two substituents, or a pharmaceutically acceptable salt of said derivatives.
L'invention a pour objet l'utilisation du guanabenz et de ses dérivés pour fabriquer des médicaments pour le traitement de la mucoviscidose et de maladies liées à un défaut d'adressage des protéines dans les cellules, ces dérivés répondant à la formule (I) : (I) dans laquelle R = H ou Cl et le groupe phényle comporte aux moins deux substituants, ou un sel pharmaceutiquement acceptable de ces dérivés.
Becq Frederic
Blondel Marc
Triboullard Deborah
Bereskin & Parr Llp/s.e.n.c.r.l.,s.r.l.
Centre National de La Recherche Scientifique (c.n.r.s.)
Universite de Poitiers
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