C - Chemistry – Metallurgy – 12 – Q
Patent
C - Chemistry, Metallurgy
12
Q
C12Q 1/70 (2006.01) C12Q 1/68 (2006.01) G01N 33/50 (2006.01)
Patent
CA 2461352
The present invention is directed to a simple and efficient methof for in vitro screening of antiviral drugs. In one embodiment, an immunoassay for measuring the amount of HCV core protein in an in vitro HCV replicating system is used. This method can be used for high throughput screening of drugs that can potentially be used to treat HCV infection in patients.
L'invention concerne un procédé simple et efficace de criblage in vitro pour médicaments antiviraux. Selon une variante, on décrit un immunoessai permettant d'évaluer la quantité de protéine nucléocapsidique de VHC dans un système de réplication de VHC in vitro. Ce procédé peut assurer un criblage à haut débit de médicaments potentiellement utilisables dans le traitement de l'infection par le VHC.
Bahl Chander
Cagnon Laurence
Lee Stephen
Niven Patrick C.
Simmen Kenneth A.
Norton Rose Or S.e.n.c.r.l. S.r.l./llp
Ortho-Clinical Diagnostics Inc.
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