A - Human Necessities – 61 – K
Patent
A - Human Necessities
61
K
A61K 31/38 (2006.01) A61K 31/135 (2006.01) A61K 31/34 (2006.01) A61K 31/35 (2006.01) A61K 31/385 (2006.01) A61K 31/39 (2006.01) A61K 31/40 (2006.01) A61K 31/41 (2006.01) A61K 31/415 (2006.01) A61K 31/445 (2006.01) A61K 31/495 (2006.01) A61K 31/535 (2006.01) A61K 31/54 (2006.01) A61K 31/55 (2006.01)
Patent
CA 2087449
2087449 9203131 PCTABS00010 A class of heterocyclic amino-alcohol compounds is described for treatment of CNS-related diseases, namely, for use as a neuroprotective agent, to reduce neurotoxic injury associated with conditions of hypoxia, anoxia or ischemia which typically follows stroke, myocardial infarct, perinatal asphyxia, or hypoglycemic events. Other examples of treatable CNS-related diseases include neurodegenerative diseases such as Parkinson's disease, Huntington's chorea and Alzheimer's disease, and also psychotic disorders such as schizophrenia. The treatment includes administration of a compound of this class alone or in a composition in an amount effective as a mediator to alter excitatory actions at the NMDA excitatory amino acid receptor complex. A compound of this class of specific interest is formula (I).
Beart Philip Mark
Gillet Claude L.
Jarrott Bevyn
Rafferty Michael F.
Roba Joseph L.
G.d. Searle & Co.
Osler Hoskin & Harcourt Llp
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