Use of high-dose oxazaphosphorine drugs for treating immune...

A - Human Necessities – 61 – K

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Details

A61K 31/675 (2006.01) A61K 38/19 (2006.01) A61P 21/04 (2006.01) A61P 25/00 (2006.01) A61P 37/00 (2006.01)

Patent

CA 2631760

This disclosure relates, at least in part, to methods of eliminating adverse immune reactions in a subject in need thereof including those associated with autoimmune diseases, allergic reactions and transplant rejection, including administration of a lymphocytotoxic non-myeloablative amount of a oxazaphosphorine drug to the subject.

La présente invention concerne, au moins en partie, des procédés permettant d'éliminer des réactions immunitaires défavorables chez un sujet qui en a besoin, y compris celles associées aux maladies auto-immunes, aux réactions allergiques et aux rejets de greffe. Lesdits procédés incluent l'administration au sujet d'une quantité lymphocytotoxique non myéloablative d'un médicament comprenant de l'oxazaphosphorine.

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