Use of histamine h4 antagonist for the treatment of...

A - Human Necessities – 61 – K

Patent

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Details

A61K 31/506 (2006.01) A61K 31/496 (2006.01) A61P 41/00 (2006.01) C07K 14/705 (2006.01)

Patent

CA 2727627

The present invention includes methods for the inhibition of post-operative adhesion formation between tissue sur-faces in a body cavity having been subjected to a surgical procedure, which methods involve administering a histamine H4 receptor antagonist, systemically, directly to tissue surfaces in the body cavity, or both, and to delivery vehicles and compositions suit-able for use for local, non-systemic administration of a drug to the body and directly to tissue within a body cavity having been subjected to a surgical procedure

La présente invention concerne des procédés dinhibition de formation dadhésion post-opératoire entre des surfaces de tissu dans une cavité corporelle ayant été soumise à une procédure chirurgicale. Lesdits procédés impliquent ladministration dun antagoniste du récepteur de lhistamine H4, systématiquement, directement sur les surfaces tissulaires dans la cavité corporelle, ou les deux, et ladministration de vecteurs et de compositions appropriés pour être utilisés dans ladministration locale non systémique dun médicament dans le corps, et directement sur un tissu situé dans une cavité corporelle ayant été soumise à une procédure chirurgicale.

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