Use of histogranin and histogranin-like compounds as...

Details Use of histogranin and histogranin-like compounds as... Use of histogranin and histogranin-like compounds as...

C - Chemistry, Metallurgy

07

K

C07K 7/08 (2006.01) A61K 31/05 (2006.01) A61K 31/4184 (2006.01) A61K 38/05 (2006.01) A61K 38/06 (2006.01) A61K 38/08 (2006.01) A61K 38/10 (2006.01) A61K 38/12 (2006.01) A61P 19/02 (2006.01) A61P 25/28 (2006.01) A61P 29/00 (2006.01) C07K 5/00 (2006.01) C07K 7/06 (2006.01) C12Q 1/02 (2006.01) G01N 33/566 (2006.01)

Patent

CA 2625940

The invention relates to the use of Histogranin-like compounds to reduce P2X7( also designed P2Z) receptor function. The invention also provides a method for the prevention and treatment of rheumatoid arthritis and a variety of diseases/disorders including inflammatory disorders and neurodegenerative diseases.

L'invention concerne l'utilisation de composés du type histogranine destinés à réduire la fonction du récepteur P2X7 (désigné également par P2Z). L'invention se rapporte également à un procédé permettant de prévenir et traiter l'arthrite rhumatoïde et une variété de maladies/troubles, parmi lesquels les troubles inflammatoires et les maladies neurodégénératives.

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