A - Human Necessities – 61 – K
Patent
A - Human Necessities
61
K
A61K 31/4725 (2006.01) A61K 31/00 (2006.01) A61K 31/341 (2006.01) A61K 31/426 (2006.01) A61K 31/472 (2006.01) A61K 31/496 (2006.01) A61K 31/513 (2006.01) A61K 38/55 (2006.01) A61K 45/06 (2006.01) A61P 1/00 (2006.01) A61P 9/10 (2006.01) A61P 17/06 (2006.01) A61P 35/00 (2006.01) A61P 37/06 (2006.01) A61P 37/08 (2006.01)
Patent
CA 2447748
The present invention relates to a method to block the invasion of normal, neoplastic inflammatory or immune cells, tissue infiltration, and/or oedema formation through inhibition or modulation of molecules and proteolytic enzymes such as -but not exclusively- MMPs, for the therapy of all diseases whose pathogenesis is related to the above processes, including tumours, non- neoplastic angioproliferative diseases, inflammatory diseases, or autoimmune diseases, the method being based on the use of inhibitors of the protease of the HIV virus (HIV-PI).
L'invention une méthode permettant de bloquer l'invasion de cellules immunitaires ou inflammatoires normales, néoplasiques, l'infiltration tissulaire, et/ou la formation d'oedème par inhibition ou modulation de molécules et d'enzymes protéolytiques notamment de métalloprotéases de matrice (MMP) afin de traiter toutes les maladies dont la pathogénèse est associée aux processus précité, à savoir les tumeurs, les maladies angioprolifératives non néoplasiques, les maladies inflammatoires, ou les maladies auto-immunes. Cette méthode est basée sur l'utilisation d'inhibiteurs de la protéase du virus VIH (VIH-PI).
Istituto Superiore Di Sanita
Marks & Clerk
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