Use of hmgb polypeptides for increasing immune responses

C - Chemistry – Metallurgy – 07 – K

Patent

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Details

IPC codes

C07K 5/00 (2006.01) A61K 39/395 (2006.01) C07K 14/47 (2006.01) C07K 16/00 (2006.01) C12N 15/00 (2006.01)

Type

Patent

Patent number

CA 2505682

Description

The present invention features polypeptides comprising an HMGB B box or a functional variant thereof that are useful for stimulating or increasing an immune response in an individual. Such polypeptides can be used in vaccine formulations and in cancer therapies.

La présente invention se rapporte à des polypeptides qui comportent une boîte HMGB B ou un variant fonctionnel d'une telle boîte et qui sont utiles pour stimuler ou accroître une réponse immunitaire chez un individu. Ces polypeptides peuvent être utilisés dans des formulations vaccinales et dans des thérapies anticancéreuses.

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