A - Human Necessities – 61 – K
Patent
A - Human Necessities
61
K
A61K 31/4412 (2006.01) A61K 31/00 (2006.01) A61K 31/122 (2006.01) A61K 31/277 (2006.01) A61K 31/341 (2006.01) A61K 31/357 (2006.01) A61K 31/415 (2006.01) A61K 31/4155 (2006.01) A61K 31/42 (2006.01) A61K 31/422 (2006.01) A61K 31/44 (2006.01) A61K 31/4439 (2006.01) A61K 45/06 (2006.01) A61P 25/24 (2006.01) A61P 25/30 (2006.01)
Patent
CA 2659424
The present invention relates to, inter alia, the use of a compound capable of inhibiting 4-hydroxyphenylpyruvate dioxygenase (HPPD) in an animal in the manufacture of a medicament for use in the treatment and/or prevention of depression. The invention also provides for the use of a compound capable of inhibiting HPPD in an animal in the manufacture of a medicament for use in the treatment of the withdrawal symptoms associated with an addictive drug which causes dopamine dependant associative learning disorders in said animal. In a particular embodiment said HPPD inhibitor is selected from the group consisting of the compound depicted as compound 1; 2; and 3.22.
La présente invention concerne, entre autres, l'utilisation d'un composé pouvant inhiber la 4-hydroxyphénylpyruvate dioxygénase (HPPD) chez un animal dans la fabrication d'un médicament destiné à être utilisé dans le traitement et/ou la prévention de la dépression. L'invention concerne également l'utilisation d'un composé pouvant inhiber l'HPPD chez un animal dans la fabrication d'un médicament destiné à être utilisé dans le traitement des symptômes de sevrage associés à une drogue engendrant la dépendance qui provoque des troubles d'apprentissage associatif dépendants de la dopamine chez ledit animal. Dans un mode de réalisation, ledit inhibiteur de l'HPPD est choisi dans le groupe constitué par le composé indiqué comme étant le composé 1; 2; et 3.22.
Posner John
Travis Kim Zachary
Gowling Lafleur Henderson Llp
Syngenta Limited
LandOfFree
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