Use of hsp70 as a regulator of enzymatic activity

A - Human Necessities – 61 – K

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A61K 38/17 (2006.01) A61P 3/00 (2006.01)

Patent

CA 2728363

The present invention concerns a method for modulating the enzymatic activity of an enzyme, wherein said enzyme interacts with BMP, said method comprising the step of administering or inducing Hsp70, or a functional fragment or variant thereof, in a form suitable for allowing interaction between BMP and Hsp70, or said functional fragment or variant thereof, and thereby modulating the enzymatic activity of an enzyme interacting with BMP.

La présente invention porte sur un procédé de modulation de l'activité enzymatique d'une enzyme, ladite enzyme entrant en interaction avec le BMP, ledit procédé comprenant l'étape d'administration ou d'induction du Hsp70, ou d'un fragment fonctionnel ou d'un variant de celui-ci, dans une forme appropriée pour permettre une interaction entre BMP et le Hsp70, ou ledit fragment fonctionnel ou variant de celui-ci, et modulant ainsi l'activité enzymatique d'une enzyme réagissant mutuellement avec le BMP.

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