Use of huntingtin and related compounds for modulating cell...

Details Use of huntingtin and related compounds for modulating cell... Use of huntingtin and related compounds for modulating cell...

A - Human Necessities

61

K

A61K 38/17 (2006.01) A61K 31/138 (2006.01) A61K 31/7088 (2006.01) A61K 39/395 (2006.01) A61K 48/00 (2006.01) A61P 25/00 (2006.01) A61P 25/28 (2006.01) A61P 35/00 (2006.01) C12Q 1/48 (2006.01)

Patent

CA 2424577

The invention provides methods and reagents for modulating cell death and cell proliferation, More specifically, the invention provides huntingtin proteins having a selected phosphorylation state and a biologically-active fragments and variants thereof for modulating cell survival.

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